KDM1A maintains genome-wide homeostasis of transcriptional enhancers

Transcriptional enhancers enable exquisite spatiotemporal control of gene expression in metazoans. Enrichment of monomethylation of histone H3 lysine 4 (H3K4me1) is a major chromatin signature of transcriptional enhancers. Lysine (K)-specific demethylase 1A (KDM1A, also known as LSD1), an H3K4me2/me...

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Detalles Bibliográficos
Autores principales: Agarwal, Saurabh, Bonefas, Katherine M., Garay, Patricia M., Brookes, Emily, Murata-Nakamura, Yumie, Porter, Robert S., Macfarlan, Todd S., Ren, Bing, Iwase, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849409/
https://www.ncbi.nlm.nih.gov/pubmed/33414108
http://dx.doi.org/10.1101/gr.234559.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849409/
https://www.ncbi.nlm.nih.gov/pubmed/33414108
http://dx.doi.org/10.1101/gr.234559.118

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