Cargando…

Hemoglobin switching in mice carrying the Klf1Nan variant

Haploinsufficiency for transcription factor KLF1 causes a variety of human erythroid phenotypes, such as the In(Lu) blood type, increased HbA2 levels, and hereditary persistence of fetal hemoglobin. Severe dominant congenital dyserythropoietic anemia IV (CDA-IV) (OMIM 613673) is associated with the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Korporaal, Anne, Gillemans, Nynke, Heshusius, Steven, Cantu, Ileana, van den Akker, Emile, van Dijk, Thamar B., von Lindern, Marieke, Philipsen, Sjaak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849558/ https://www.ncbi.nlm.nih.gov/pubmed/32467144 http://dx.doi.org/10.3324/haematol.2019.239830

Ejemplares similares

The mouse KLF1 Nan variant impairs nuclear condensation and erythroid maturation
por: Cantú, Ileana, et al.
Publicado: (2019)

Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts
por: Heshusius, Steven, et al.
Publicado: (2022)

Haploinsufficiency for the erythroid transcription factor KLF1 causes Hereditary Persistence of Fetal Hemoglobin
por: Borg, Joseph, et al.
Publicado: (2010)

CD14+ monocytes repress gamma globin expression at early stages of erythropoiesis
por: Heshusius, Steven, et al.
Publicado: (2021)

Novel variants in Krueppel like factor 1 that cause persistence of fetal hemoglobin in In(Lu) individuals
por: Eernstman, Jesse, et al.
Publicado: (2021)

Iron-loaded deferiprone can support full hemoglobinization of cultured red blood cells
por: Gallego-Murillo, Joan Sebastián, et al.
Publicado: (2023)

Epigenetic Silencing of Spermatocyte-Specific and Neuronal Genes by SUMO Modification of the Transcription Factor Sp3
por: Stielow, Bastian, et al.
Publicado: (2010)

Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors
por: Gilmour, Jane, et al.
Publicado: (2019)

The Shape Shifting Story of Reticulocyte Maturation
por: Ovchynnikova, Elina, et al.
Publicado: (2018)

Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis
por: Nébor, Danitza, et al.
Publicado: (2018)

Comparative studies of catalytic pathways for Streptococcus pneumoniae sialidases NanA, NanB and NanC
por: Xiao, Kela, et al.
Publicado: (2019)

Targeted Protein Degradation as a Promising Tool for Epigenetic Upregulation of Fetal Hemoglobin
por: J. Verheul, Thijs C., et al.
Publicado: (2020)

S277: IPSC DISEASE MODELS TO STUDY AND TREAT DIAMOND-BLACKFAN ANEMIA SYNDROME (DBAS)
por: Clark, Chantal, et al.
Publicado: (2023)

Specificity Protein 2 (Sp2) Is Essential for Mouse Development and Autonomous Proliferation of Mouse Embryonic Fibroblasts
por: Baur, Frank, et al.
Publicado: (2010)

N'on nan kobijnd'ue n'an tzjon noan = Los usos de la madera entre los amuzgos
por: Cruz Hernández, Modesta
Publicado: (1993)

Assessing the function of pneumococcal neuraminidases NanA, NanB and NanC in in vitro and in vivo lung infection models using monoclonal antibodies
por: Janesch, Philipp, et al.
Publicado: (2018)

Circular RNA expression in human hematopoietic cells is widespread and cell-type specific
por: Nicolet, Benoit P, et al.
Publicado: (2018)

Study of the Influence of NanOx Parameters
por: Monini, Caterina, et al.
Publicado: (2018)

NANS-CDG: Delineation of the Genetic, Biochemical, and Clinical Spectrum
por: den Hollander, Bibiche, et al.
Publicado: (2021)

FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1
por: Bakker, Walbert J., et al.
Publicado: (2004)

Epidemiology of fragility hip fractures in Nan, Thailand
por: Sucharitpongpan, Worapong, et al.
Publicado: (2019)

Mechanical Stress Induces Ca(2+)-Dependent Signal Transduction in Erythroblasts and Modulates Erythropoiesis
por: Aglialoro, Francesca, et al.
Publicado: (2021)

Expansion and differentiation of ex vivo cultured erythroblasts in scalable stirred bioreactors
por: Gallego‐Murillo, Joan Sebastián, et al.
Publicado: (2022)

KLF1 gene and borderline hemoglobin A(2) in Saudi population
por: Borgio, J. Francis, et al.
Publicado: (2017)

Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies
por: Loucari, Constantinos C., et al.
Publicado: (2018)

Circular RNAs exhibit limited evidence for translation, or translation regulation of the mRNA counterpart in terminal hematopoiesis
por: Nicolet, Benoit P., et al.
Publicado: (2022)

Zhong Nan-Shan: leader of clinical research in China
por: Cheng, Margaret Harris
Publicado: (2009)

Spatial Variation of Cladophora Epiphytes in the Nan River, Thailand
por: Ruen-Pham, Karnjana, et al.
Publicado: (2021)

SMS Nanning and RWTH Aachen: In Memory of Vladimir Gerdt
por: Wang, Dongming
Publicado: (2022)

Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B
por: Papadopoulos, Petros, et al.
Publicado: (2020)

Remarkable Phytochemical Characteristics of Chi-Nan Agarwood Induced from New-Found Chi-Nan Germplasm of Aquilaria sinensis Compared with Ordinary Agarwood
por: Yu, Meng, et al.
Publicado: (2021)

Characterization of NanR Regulation of Sialidase Production, Sporulation and Enterotoxin Production by Clostridium perfringens Type F Strains Carrying a Chromosomal Enterotoxin Gene
por: Li, Jihong, et al.
Publicado: (2022)

Grsf1-Induced Translation of the SNARE Protein Use1 Is Required for Expansion of the Erythroid Compartment
por: Nieradka, Andrzej, et al.
Publicado: (2014)

Structure of the catalytic domain of Streptococcus pneumoniae sialidase NanA
por: Xu, Guogang, et al.
Publicado: (2008)

Role of Pneumococcal NanA Neuraminidase Activity in Peripheral Blood
por: Syed, Shahan, et al.
Publicado: (2019)

Giants in Chest Medicine: Professor Nan-shan Zhong, MD
por: Guan, Wei-jie
Publicado: (2018)

Chi-Nan Hu—Pioneer of Chinese neuroscience and cognitive science
por: Wang, Yunjin, et al.
Publicado: (2019)

Nan Yan: Innate immune signaling goes beyond viral
por: Morgado-Palacin, Lucia
Publicado: (2021)

SulfoxFluor-enabled deoxyazidation of alcohols with NaN(3)
por: Guo, Junkai, et al.
Publicado: (2022)

Genetic and functional characterization of the NanA sialidase from Clostridium chauvoei
por: Vilei, Edy M, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_bkk33rbbj7dm4lccg100hctakl