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Hemoglobin switching in mice carrying the Klf1Nan variant

Haploinsufficiency for transcription factor KLF1 causes a variety of human erythroid phenotypes, such as the In(Lu) blood type, increased HbA2 levels, and hereditary persistence of fetal hemoglobin. Severe dominant congenital dyserythropoietic anemia IV (CDA-IV) (OMIM 613673) is associated with the...

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Detalles Bibliográficos
Autores principales:	Korporaal, Anne, Gillemans, Nynke, Heshusius, Steven, Cantu, Ileana, van den Akker, Emile, van Dijk, Thamar B., von Lindern, Marieke, Philipsen, Sjaak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849558/ https://www.ncbi.nlm.nih.gov/pubmed/32467144 http://dx.doi.org/10.3324/haematol.2019.239830

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