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uPA-mediated plasminogen activation is enhanced by polyphosphate

Tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA) differ in their modes of action. Efficient tPA-mediated plasminogen activation requires binding to fibrin. In contrast, uPA is fibrin independent and activates plasminogen in solution or when associated with its cellular re...

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Detalles Bibliográficos
Autores principales:	Whyte, Claire S., Mutch, Nicola J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849561/ https://www.ncbi.nlm.nih.gov/pubmed/32029503 http://dx.doi.org/10.3324/haematol.2019.237966

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