Induction of erythroferrone in healthy humans by micro-dose recombinant erythropoietin or high-altitude exposure

The erythropoietin (Epo)-erythroferrone (ERFE)-hepcidin axis coordinates erythropoiesis and iron homeostasis. While mouse studies have established that Epo-induced ERFE production represses hepcidin synthesis by inhibiting hepatic BMP/SMAD signaling, evidence for the role of ERFE in humans is limite...

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Detalles Bibliográficos
Autores principales: Robach, Paul, Gammella, Elena, Recalcati, Stefania, Girelli, Domenico, Castagna, Annalisa, Roustit, Matthieu, Lundby, Carsten, Lundby, Anne-Kristine, Bouzat, Pierre, Verges, Samuel, Sechaud, Guillaume, Banco, Pierluigi, Uhr, Mario, Cornu, Catherine, Sallet, Pierre, Cairo, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849588/
https://www.ncbi.nlm.nih.gov/pubmed/31919080
http://dx.doi.org/10.3324/haematol.2019.233874

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