Donor-Derived Myeloid Heme Oxygenase-1 Controls the Development of Graft-Versus-Host Disease

Graft-versus-host disease (GVHD) remains a major clinical drawback of allogeneic hematopoietic stem cell transplantation (HSCT). Here, we investigated how the stress responsive heme catabolizing enzyme heme oxygenase-1 (HO-1, encoded by HMOX1) regulates GVHD in response to allogeneic hematopoietic s...

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Detalles Bibliográficos
Autores principales: Spilleboudt, Chloé, De Wilde, Virginie, Lewalle, Philippe, Cabanne, Ludovic, Leclerc, Mathieu, Beckerich, Florence, Bories, Dominique, Cardoso, Silvia, Soares, Miguel P., Vokaer, Benoît, Hougardy, Jean-Michel, Flamand, Véronique, Racapé, Judith, Abramowicz, Marc, Maury, Sébastien, Le Moine, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849683/
https://www.ncbi.nlm.nih.gov/pubmed/33537027
http://dx.doi.org/10.3389/fimmu.2020.579151

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