Niche-specific MHC II and PD-L1 regulate CD4(+)CD8αα(+) intraepithelial lymphocyte differentiation

Conventional CD4(+) T cells are differentiated into CD4(+)CD8αα(+) intraepithelial lymphocytes (IELs) in the intestine; however, the roles of intestinal epithelial cells (IECs) are poorly understood. Here, we showed that IECs expressed MHC class II (MHC II) and programmed death–ligand 1 (PD-L1) indu...

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Detalles Bibliográficos
Autores principales: Moon, Sookjin, Park, Yunji, Hyeon, Sumin, Kim, Young-Min, Kim, Ji-Hae, Kim, Hyekang, Park, Subin, Lee, Kun-Joo, Koo, Bon-Kyoung, Ha, Sang-Jun, Lee, Seung-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849820/
https://www.ncbi.nlm.nih.gov/pubmed/33533917
http://dx.doi.org/10.1084/jem.20201665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849820/
https://www.ncbi.nlm.nih.gov/pubmed/33533917
http://dx.doi.org/10.1084/jem.20201665

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