Systematic identification of non-coding somatic single nucleotide variants associated with altered transcription and DNA methylation in adult and pediatric cancers

Whole-genome sequencing combined with transcriptomics can reveal impactful non-coding single nucleotide variants (SNVs) in cancer. Here, we developed an integrative analytical approach that, as a first step, identifies genes altered in expression or DNA methylation in association with nearby somatic...

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Detalles Bibliográficos
Autores principales: Chen, Fengju, Zhang, Yiqun, Creighton, Chad J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Cancer Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849833/
https://www.ncbi.nlm.nih.gov/pubmed/33554123
http://dx.doi.org/10.1093/narcan/zcab001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849833/
https://www.ncbi.nlm.nih.gov/pubmed/33554123
http://dx.doi.org/10.1093/narcan/zcab001

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