Heat shock proteins and small nucleolar RNAs are dysregulated in a Drosophila model for feline hypertrophic cardiomyopathy

In cats, mutations in myosin binding protein C (encoded by the MYBPC3 gene) have been associated with hypertrophic cardiomyopathy (HCM). However, the molecular mechanisms linking these mutations to HCM remain unknown. Here, we establish Drosophila melanogaster as a model to understand this connectio...

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Detalles Bibliográficos
Autores principales: Tallo, Christian A, Duncan, Laura H, Yamamoto, Akihiko H, Slaydon, Joshua D, Arya, Gunjan H, Turlapati, Lavanya, Mackay, Trudy F C, Carbone, Mary A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849908/
https://www.ncbi.nlm.nih.gov/pubmed/33561224
http://dx.doi.org/10.1093/g3journal/jkaa014

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