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Favorable role of IDH1/2 mutations aided with MGMT promoter gene methylation in the outcome of patients with malignant glioma

AIM: The implications of molecular biomarkers IDH1/2 mutations and MGMT gene promoter methylation were evaluated for prognostic outcome of glioma patients. MATERIALS & METHODS: Glioma cases were analyzed for IDH1/2 mutations and MGMT promoter methylation by DNA sequencing and methylation-specifi...

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Detalles Bibliográficos
Autores principales: Pandith, Arshad A, Qasim, Iqbal, Baba, Shahid M, Koul, Aabid, Zahoor, Wani, Afroze, Dil, Lateef, Adil, Manzoor, Usma, Bhat, Ina A, Sanadhya, Dheera, Bhat, Abdul R, Ramzan, Altaf U, Mohammad, Fozia, Anwar, Iqra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849969/
https://www.ncbi.nlm.nih.gov/pubmed/33552543
http://dx.doi.org/10.2144/fsoa-2020-0057