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Measuring cerebral perfusion with [(11)C]-PiB R1 in Down syndrome: associations with amyloid burden and longitudinal cognitive decline

Positron emission tomography imaging of glucose hypometabolism and amyloid deposition are two well-established methods to evaluate preclinical changes in Alzheimer’s disease and people with Down syndrome. However, the use of both imaging modalities may overburden participants, particularly those wit...

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Detalles Bibliográficos
Autores principales: Mak, Elijah, Grigorova, Monika, Beresford-Webb, Jessica, Malpetti, Maura, Walpert, Madeline, Brown, Stephanie, Jones, Elizabeth, Clare, Isabel, Hong, Young T, Fryer, Tim D, Coles, Jonathan P, Aigbirhio, Franklin I, Menon, David K, Nestor, Peter J, Holland, Anthony J, Zaman, Shahid H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849981/
https://www.ncbi.nlm.nih.gov/pubmed/33543138
http://dx.doi.org/10.1093/braincomms/fcaa198

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