Effectiveness and Safety of Biodegradable Calcium Sulfate Antibiotic Beads as Adjuvant Therapy in Vascular Graft Infections

This is a retrospective cohort study evaluating the safety and effectiveness of biodegradable calcium sulfate antibiotic beads in vascular graft infections compared with standard of care. No differences in acute kidney injury or hypercalcemia were observed between the cohorts. Recurrence of infectio...

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Detalles Bibliográficos
Autores principales: Doub, James B, Bork, Jacqueline T, Heil, Emily, Stafford, Kristen, Banoub, Mary, Karwowski, John K, Toursavadkohi, Shahab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849989/
https://www.ncbi.nlm.nih.gov/pubmed/33553481
http://dx.doi.org/10.1093/ofid/ofaa650
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author Doub, James B
Bork, Jacqueline T
Heil, Emily
Stafford, Kristen
Banoub, Mary
Karwowski, John K
Toursavadkohi, Shahab
author_facet Doub, James B
Bork, Jacqueline T
Heil, Emily
Stafford, Kristen
Banoub, Mary
Karwowski, John K
Toursavadkohi, Shahab
author_sort Doub, James B
collection PubMed
description This is a retrospective cohort study evaluating the safety and effectiveness of biodegradable calcium sulfate antibiotic beads in vascular graft infections compared with standard of care. No differences in acute kidney injury or hypercalcemia were observed between the cohorts. Recurrence of infection did not occur in the 13-patient bead cohort compared with 14 patients who had recurrence in the 45-patient nonbead cohort with a number needed to treat of 4.0.
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spelling pubmed-78499892021-02-05 Effectiveness and Safety of Biodegradable Calcium Sulfate Antibiotic Beads as Adjuvant Therapy in Vascular Graft Infections Doub, James B Bork, Jacqueline T Heil, Emily Stafford, Kristen Banoub, Mary Karwowski, John K Toursavadkohi, Shahab Open Forum Infect Dis Brief Reports This is a retrospective cohort study evaluating the safety and effectiveness of biodegradable calcium sulfate antibiotic beads in vascular graft infections compared with standard of care. No differences in acute kidney injury or hypercalcemia were observed between the cohorts. Recurrence of infection did not occur in the 13-patient bead cohort compared with 14 patients who had recurrence in the 45-patient nonbead cohort with a number needed to treat of 4.0. Oxford University Press 2021-01-04 /pmc/articles/PMC7849989/ /pubmed/33553481 http://dx.doi.org/10.1093/ofid/ofaa650 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Doub, James B
Bork, Jacqueline T
Heil, Emily
Stafford, Kristen
Banoub, Mary
Karwowski, John K
Toursavadkohi, Shahab
Effectiveness and Safety of Biodegradable Calcium Sulfate Antibiotic Beads as Adjuvant Therapy in Vascular Graft Infections
title Effectiveness and Safety of Biodegradable Calcium Sulfate Antibiotic Beads as Adjuvant Therapy in Vascular Graft Infections
title_full Effectiveness and Safety of Biodegradable Calcium Sulfate Antibiotic Beads as Adjuvant Therapy in Vascular Graft Infections
title_fullStr Effectiveness and Safety of Biodegradable Calcium Sulfate Antibiotic Beads as Adjuvant Therapy in Vascular Graft Infections
title_full_unstemmed Effectiveness and Safety of Biodegradable Calcium Sulfate Antibiotic Beads as Adjuvant Therapy in Vascular Graft Infections
title_short Effectiveness and Safety of Biodegradable Calcium Sulfate Antibiotic Beads as Adjuvant Therapy in Vascular Graft Infections
title_sort effectiveness and safety of biodegradable calcium sulfate antibiotic beads as adjuvant therapy in vascular graft infections
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849989/
https://www.ncbi.nlm.nih.gov/pubmed/33553481
http://dx.doi.org/10.1093/ofid/ofaa650
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