Cargando…

Intake of Sugar-Sweetened and Low-Calorie Sweetened Beverages and Risk of Cardiovascular Disease: A Meta-Analysis and Systematic Review

The long-term associations between the consumption of sugar-sweetened beverages (SSBs) and low-calorie sweetened beverages (LCSBs) with cardiovascular diseases (CVDs) remains inconsistent. To synthesize the evidence, we conducted a meta-analysis of prospective cohort studies published up to 1 Decemb...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Jiawei, Zhu, Yalun, Malik, Vasanti, Li, Xiaoqin, Peng, Xiaolin, Zhang, Fang Fang, Shan, Zhilei, Liu, Liegang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850046/
https://www.ncbi.nlm.nih.gov/pubmed/32696948
http://dx.doi.org/10.1093/advances/nmaa084
_version_ 1783645398527639552
author Yin, Jiawei
Zhu, Yalun
Malik, Vasanti
Li, Xiaoqin
Peng, Xiaolin
Zhang, Fang Fang
Shan, Zhilei
Liu, Liegang
author_facet Yin, Jiawei
Zhu, Yalun
Malik, Vasanti
Li, Xiaoqin
Peng, Xiaolin
Zhang, Fang Fang
Shan, Zhilei
Liu, Liegang
author_sort Yin, Jiawei
collection PubMed
description The long-term associations between the consumption of sugar-sweetened beverages (SSBs) and low-calorie sweetened beverages (LCSBs) with cardiovascular diseases (CVDs) remains inconsistent. To synthesize the evidence, we conducted a meta-analysis of prospective cohort studies published up to 1 December, 2019 on the associations between SSB and LCSB intake and the risk of CVD incidence and mortality. Out of 5301 articles retrieved from our literature search, 11 articles evaluating the consumption of SSBs (16,915 incident CVD cases, 18,042 CVD deaths) and 8 articles evaluating the consumption of LCSBs (18,077 incident CVD cases, 14,114 CVD deaths) were included in the meta-analysis. A 1 serving/d increment of SSBs was associated with an 8% (RR: 1.08; 95% CI: 1.02, 1.14, I(2) = 43.0%) and 8% (RR: 1.08; 95% CI: 1.04, 1.13, I(2) = 40.6%) higher risk of CVD incidence and CVD mortality, respectively. A 1 serving/d increment of LCSBs was associated with a 7% (RR: 1.07; 95% CI: 1.05, 1.10, I(2) = 0.0%) higher risk of CVD incidence. The association between LCSBs and CVD mortality appeared to be nonlinear (P = 0.003 for nonlinearity) with significant associations observed at high intake levels (>2 servings/d). Under an assumption of causality, the consumption of SSBs may be linked to 9.3% (95% CI: 6.6%, 11.9%) of predicted CVD incidence in the USA from 2015 to 2025, among men and nonpregnant women, who were aged 40–79 y in 2015–2016. The habitual consumption of SSBs was associated with a higher risk of CVD morbidity and mortality in a dose-response manner. LCSBs were also associated with a higher risk of these outcomes, however, the interpretation of these findings may be complicated by reverse causation and residual confounding.
format Online
Article
Text
id pubmed-7850046
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-78500462021-02-04 Intake of Sugar-Sweetened and Low-Calorie Sweetened Beverages and Risk of Cardiovascular Disease: A Meta-Analysis and Systematic Review Yin, Jiawei Zhu, Yalun Malik, Vasanti Li, Xiaoqin Peng, Xiaolin Zhang, Fang Fang Shan, Zhilei Liu, Liegang Adv Nutr Review The long-term associations between the consumption of sugar-sweetened beverages (SSBs) and low-calorie sweetened beverages (LCSBs) with cardiovascular diseases (CVDs) remains inconsistent. To synthesize the evidence, we conducted a meta-analysis of prospective cohort studies published up to 1 December, 2019 on the associations between SSB and LCSB intake and the risk of CVD incidence and mortality. Out of 5301 articles retrieved from our literature search, 11 articles evaluating the consumption of SSBs (16,915 incident CVD cases, 18,042 CVD deaths) and 8 articles evaluating the consumption of LCSBs (18,077 incident CVD cases, 14,114 CVD deaths) were included in the meta-analysis. A 1 serving/d increment of SSBs was associated with an 8% (RR: 1.08; 95% CI: 1.02, 1.14, I(2) = 43.0%) and 8% (RR: 1.08; 95% CI: 1.04, 1.13, I(2) = 40.6%) higher risk of CVD incidence and CVD mortality, respectively. A 1 serving/d increment of LCSBs was associated with a 7% (RR: 1.07; 95% CI: 1.05, 1.10, I(2) = 0.0%) higher risk of CVD incidence. The association between LCSBs and CVD mortality appeared to be nonlinear (P = 0.003 for nonlinearity) with significant associations observed at high intake levels (>2 servings/d). Under an assumption of causality, the consumption of SSBs may be linked to 9.3% (95% CI: 6.6%, 11.9%) of predicted CVD incidence in the USA from 2015 to 2025, among men and nonpregnant women, who were aged 40–79 y in 2015–2016. The habitual consumption of SSBs was associated with a higher risk of CVD morbidity and mortality in a dose-response manner. LCSBs were also associated with a higher risk of these outcomes, however, the interpretation of these findings may be complicated by reverse causation and residual confounding. Oxford University Press 2020-07-22 /pmc/articles/PMC7850046/ /pubmed/32696948 http://dx.doi.org/10.1093/advances/nmaa084 Text en Copyright © The Author(s) on behalf of the American Society for Nutrition 2020. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Review
Yin, Jiawei
Zhu, Yalun
Malik, Vasanti
Li, Xiaoqin
Peng, Xiaolin
Zhang, Fang Fang
Shan, Zhilei
Liu, Liegang
Intake of Sugar-Sweetened and Low-Calorie Sweetened Beverages and Risk of Cardiovascular Disease: A Meta-Analysis and Systematic Review
title Intake of Sugar-Sweetened and Low-Calorie Sweetened Beverages and Risk of Cardiovascular Disease: A Meta-Analysis and Systematic Review
title_full Intake of Sugar-Sweetened and Low-Calorie Sweetened Beverages and Risk of Cardiovascular Disease: A Meta-Analysis and Systematic Review
title_fullStr Intake of Sugar-Sweetened and Low-Calorie Sweetened Beverages and Risk of Cardiovascular Disease: A Meta-Analysis and Systematic Review
title_full_unstemmed Intake of Sugar-Sweetened and Low-Calorie Sweetened Beverages and Risk of Cardiovascular Disease: A Meta-Analysis and Systematic Review
title_short Intake of Sugar-Sweetened and Low-Calorie Sweetened Beverages and Risk of Cardiovascular Disease: A Meta-Analysis and Systematic Review
title_sort intake of sugar-sweetened and low-calorie sweetened beverages and risk of cardiovascular disease: a meta-analysis and systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850046/
https://www.ncbi.nlm.nih.gov/pubmed/32696948
http://dx.doi.org/10.1093/advances/nmaa084
work_keys_str_mv AT yinjiawei intakeofsugarsweetenedandlowcaloriesweetenedbeveragesandriskofcardiovasculardiseaseametaanalysisandsystematicreview
AT zhuyalun intakeofsugarsweetenedandlowcaloriesweetenedbeveragesandriskofcardiovasculardiseaseametaanalysisandsystematicreview
AT malikvasanti intakeofsugarsweetenedandlowcaloriesweetenedbeveragesandriskofcardiovasculardiseaseametaanalysisandsystematicreview
AT lixiaoqin intakeofsugarsweetenedandlowcaloriesweetenedbeveragesandriskofcardiovasculardiseaseametaanalysisandsystematicreview
AT pengxiaolin intakeofsugarsweetenedandlowcaloriesweetenedbeveragesandriskofcardiovasculardiseaseametaanalysisandsystematicreview
AT zhangfangfang intakeofsugarsweetenedandlowcaloriesweetenedbeveragesandriskofcardiovasculardiseaseametaanalysisandsystematicreview
AT shanzhilei intakeofsugarsweetenedandlowcaloriesweetenedbeveragesandriskofcardiovasculardiseaseametaanalysisandsystematicreview
AT liuliegang intakeofsugarsweetenedandlowcaloriesweetenedbeveragesandriskofcardiovasculardiseaseametaanalysisandsystematicreview