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AmpliCI: a high-resolution model-based approach for denoising Illumina amplicon data

MOTIVATION: Next-generation amplicon sequencing is a powerful tool for investigating microbial communities. A main challenge is to distinguish true biological variants from errors caused by amplification and sequencing. In traditional analyses, such errors are eliminated by clustering reads within a...

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Detalles Bibliográficos
Autores principales: Peng, Xiyu, Dorman, Karin S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850112/
https://www.ncbi.nlm.nih.gov/pubmed/32697845
http://dx.doi.org/10.1093/bioinformatics/btaa648

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