Tumour necrosis factor induces increased production of extracellular amyloid-β- and α-synuclein-containing aggregates by human Alzheimer’s disease neurons

In addition to increased aberrant protein aggregation, inflammation has been proposed as a key element in the pathogenesis and progression of Alzheimer’s disease. How inflammation interacts with other disease pathways and how protein aggregation increases during disease are not clear. We used single...

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Detalles Bibliográficos
Autores principales: Whiten, Daniel R, Brownjohn, Philip W, Moore, Steven, De, Suman, Strano, Alessio, Zuo, Yukun, Haneklaus, Moritz, Klenerman, David, Livesey, Frederick J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850285/
https://www.ncbi.nlm.nih.gov/pubmed/33543132
http://dx.doi.org/10.1093/braincomms/fcaa146

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