Inhibition of Bone Morphogenetic Protein 2 Suppresses the Stemness Maintenance of Cancer Stem Cells in Hepatocellular Carcinoma via the MAPK/ERK Pathway

BACKGROUND: Hepatocellular carcinoma (HCC) remains a life-threatening malignant tumor. Cancer stem cells (CSCs) harbor tumor-initiating capacity and can be used as a therapeutic target for human malignancies. Bone morphogenetic proteins (BMPs) play a regulatory role in CSCs. This study investigated...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Juncheng, Guo, Min, Zheng, Jinfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850411/
https://www.ncbi.nlm.nih.gov/pubmed/33536785
http://dx.doi.org/10.2147/CMAR.S281969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850411/
https://www.ncbi.nlm.nih.gov/pubmed/33536785
http://dx.doi.org/10.2147/CMAR.S281969

Ejemplares similares