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Aggregative cycles evolve as a solution to conflicts in social investment

Multicellular organization is particularly vulnerable to conflicts between different cell types when the body forms from initially isolated cells, as in aggregative multicellular microbes. Like other functions of the multicellular phase, coordinated collective movement can be undermined by conflicts...

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Detalles Bibliográficos
Autores principales: Miele, Leonardo, De Monte, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850506/
https://www.ncbi.nlm.nih.gov/pubmed/33471791
http://dx.doi.org/10.1371/journal.pcbi.1008617
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author Miele, Leonardo
De Monte, Silvia
author_facet Miele, Leonardo
De Monte, Silvia
author_sort Miele, Leonardo
collection PubMed
description Multicellular organization is particularly vulnerable to conflicts between different cell types when the body forms from initially isolated cells, as in aggregative multicellular microbes. Like other functions of the multicellular phase, coordinated collective movement can be undermined by conflicts between cells that spend energy in fuelling motion and ‘cheaters’ that get carried along. The evolutionary stability of collective behaviours against such conflicts is typically addressed in populations that undergo extrinsically imposed phases of aggregation and dispersal. Here, via a shift in perspective, we propose that aggregative multicellular cycles may have emerged as a way to temporally compartmentalize social conflicts. Through an eco-evolutionary mathematical model that accounts for individual and collective strategies of resource acquisition, we address regimes where different motility types coexist. Particularly interesting is the oscillatory regime that, similarly to life cycles of aggregative multicellular organisms, alternates on the timescale of several cell generations phases of prevalent solitary living and starvation-triggered aggregation. Crucially, such self-organized oscillations emerge as a result of evolution of cell traits associated to conflict escalation within multicellular aggregates.
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spelling pubmed-78505062021-02-09 Aggregative cycles evolve as a solution to conflicts in social investment Miele, Leonardo De Monte, Silvia PLoS Comput Biol Research Article Multicellular organization is particularly vulnerable to conflicts between different cell types when the body forms from initially isolated cells, as in aggregative multicellular microbes. Like other functions of the multicellular phase, coordinated collective movement can be undermined by conflicts between cells that spend energy in fuelling motion and ‘cheaters’ that get carried along. The evolutionary stability of collective behaviours against such conflicts is typically addressed in populations that undergo extrinsically imposed phases of aggregation and dispersal. Here, via a shift in perspective, we propose that aggregative multicellular cycles may have emerged as a way to temporally compartmentalize social conflicts. Through an eco-evolutionary mathematical model that accounts for individual and collective strategies of resource acquisition, we address regimes where different motility types coexist. Particularly interesting is the oscillatory regime that, similarly to life cycles of aggregative multicellular organisms, alternates on the timescale of several cell generations phases of prevalent solitary living and starvation-triggered aggregation. Crucially, such self-organized oscillations emerge as a result of evolution of cell traits associated to conflict escalation within multicellular aggregates. Public Library of Science 2021-01-20 /pmc/articles/PMC7850506/ /pubmed/33471791 http://dx.doi.org/10.1371/journal.pcbi.1008617 Text en © 2021 Miele, De Monte http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Miele, Leonardo
De Monte, Silvia
Aggregative cycles evolve as a solution to conflicts in social investment
title Aggregative cycles evolve as a solution to conflicts in social investment
title_full Aggregative cycles evolve as a solution to conflicts in social investment
title_fullStr Aggregative cycles evolve as a solution to conflicts in social investment
title_full_unstemmed Aggregative cycles evolve as a solution to conflicts in social investment
title_short Aggregative cycles evolve as a solution to conflicts in social investment
title_sort aggregative cycles evolve as a solution to conflicts in social investment
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850506/
https://www.ncbi.nlm.nih.gov/pubmed/33471791
http://dx.doi.org/10.1371/journal.pcbi.1008617
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