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Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection
New tools are needed to support pre-exposure prophylaxis (PrEP) adherence for human immunodeficiency virus (HIV) prevention, including those that enable real-time feedback. In a large, completed PrEP trial, adequate urine tenofovir levels measured using a novel immunoassay predicted HIV protection a...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850546/ https://www.ncbi.nlm.nih.gov/pubmed/33527128 http://dx.doi.org/10.1093/cid/ciaa785 |
| _version_ | 1783645463012966400 |
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| author | Stalter, Randy M Baeten, Jared M Donnell, Deborah Spinelli, Matthew A Glidden, David V Rodrigues, Warren C Wang, Guohong Vincent, Michael Mugo, Nelly Mujugira, Andrew Marzinke, Mark Hendrix, Craig Gandhi, Monica |
| author_facet | Stalter, Randy M Baeten, Jared M Donnell, Deborah Spinelli, Matthew A Glidden, David V Rodrigues, Warren C Wang, Guohong Vincent, Michael Mugo, Nelly Mujugira, Andrew Marzinke, Mark Hendrix, Craig Gandhi, Monica |
| author_sort | Stalter, Randy M |
| collection | PubMed |
| description | New tools are needed to support pre-exposure prophylaxis (PrEP) adherence for human immunodeficiency virus (HIV) prevention, including those that enable real-time feedback. In a large, completed PrEP trial, adequate urine tenofovir levels measured using a novel immunoassay predicted HIV protection and showed good sensitivity and specificity for detectable plasma tenofovir. |
| format | Online Article Text |
| id | pubmed-7850546 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-78505462021-02-03 Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection Stalter, Randy M Baeten, Jared M Donnell, Deborah Spinelli, Matthew A Glidden, David V Rodrigues, Warren C Wang, Guohong Vincent, Michael Mugo, Nelly Mujugira, Andrew Marzinke, Mark Hendrix, Craig Gandhi, Monica Clin Infect Dis Brief Reports New tools are needed to support pre-exposure prophylaxis (PrEP) adherence for human immunodeficiency virus (HIV) prevention, including those that enable real-time feedback. In a large, completed PrEP trial, adequate urine tenofovir levels measured using a novel immunoassay predicted HIV protection and showed good sensitivity and specificity for detectable plasma tenofovir. Oxford University Press 2020-06-22 /pmc/articles/PMC7850546/ /pubmed/33527128 http://dx.doi.org/10.1093/cid/ciaa785 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Brief Reports Stalter, Randy M Baeten, Jared M Donnell, Deborah Spinelli, Matthew A Glidden, David V Rodrigues, Warren C Wang, Guohong Vincent, Michael Mugo, Nelly Mujugira, Andrew Marzinke, Mark Hendrix, Craig Gandhi, Monica Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection |
| title | Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection |
| title_full | Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection |
| title_fullStr | Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection |
| title_full_unstemmed | Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection |
| title_short | Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection |
| title_sort | urine tenofovir levels measured using a novel immunoassay predict human immunodeficiency virus protection |
| topic | Brief Reports |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850546/ https://www.ncbi.nlm.nih.gov/pubmed/33527128 http://dx.doi.org/10.1093/cid/ciaa785 |
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