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Carrier-Induced Hyporesponsiveness to Pneumococcal Conjugate Vaccines: Unraveling the Influence of Serotypes, Timing, and Previous Vaccine Dose

BACKGROUND: Pneumococcal conjugate vaccines (PCVs) elicit lower immune response against serotypes carried before or at the time of vaccination (hyporesponsiveness) in infants. The limited studies conducted to date did not permit comprehensive insights regarding this phenomenon. This study, the large...

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Detalles Bibliográficos
Autores principales: Dagan, Ron, Jiang, Qin, Juergens, Christine, Trammel, James, Gruber, William C, Scott, Daniel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850554/
https://www.ncbi.nlm.nih.gov/pubmed/31995183
http://dx.doi.org/10.1093/cid/ciaa083