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Carrier-Induced Hyporesponsiveness to Pneumococcal Conjugate Vaccines: Unraveling the Influence of Serotypes, Timing, and Previous Vaccine Dose
BACKGROUND: Pneumococcal conjugate vaccines (PCVs) elicit lower immune response against serotypes carried before or at the time of vaccination (hyporesponsiveness) in infants. The limited studies conducted to date did not permit comprehensive insights regarding this phenomenon. This study, the large...
Autores principales: | Dagan, Ron, Jiang, Qin, Juergens, Christine, Trammel, James, Gruber, William C, Scott, Daniel A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850554/ https://www.ncbi.nlm.nih.gov/pubmed/31995183 http://dx.doi.org/10.1093/cid/ciaa083 |
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