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Stability analysis and optimal control of Covid-19 pandemic SEIQR fractional mathematical model with harmonic mean type incidence rate and treatment

In the present work, we investigated the transmission dynamics of fractional order SARS-CoV-2 mathematical model with the help of Susceptible [Formula: see text] , Exposed [Formula: see text] , Infected [Formula: see text] , Quarantine [Formula: see text] , and Recovered [Formula: see text]. The aim...

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Autores principales: Sinan, Muhammad, Ali, Amjad, Shah, Kamal, Assiri, Taghreed A., Nofal, Taher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850626/
https://www.ncbi.nlm.nih.gov/pubmed/33552882
http://dx.doi.org/10.1016/j.rinp.2021.103873
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author Sinan, Muhammad
Ali, Amjad
Shah, Kamal
Assiri, Taghreed A.
Nofal, Taher A.
author_facet Sinan, Muhammad
Ali, Amjad
Shah, Kamal
Assiri, Taghreed A.
Nofal, Taher A.
author_sort Sinan, Muhammad
collection PubMed
description In the present work, we investigated the transmission dynamics of fractional order SARS-CoV-2 mathematical model with the help of Susceptible [Formula: see text] , Exposed [Formula: see text] , Infected [Formula: see text] , Quarantine [Formula: see text] , and Recovered [Formula: see text]. The aims of this work is to investigate the stability and optimal control of the concerned mathematical model for both local and global stability by third additive compound matrix approach and we also obtained threshold value by the next generation approach. The author’s visualized the desired results graphically. We also control each of the population of underlying model with control variables by optimal control strategies with Pontryagin’s maximum Principle and obtained the desired numerical results by using the homotopy perturbation method. The proposed model is locally asymptotically unstable, while stable globally asymptotically on endemic equilibrium. We also explored the results graphically in numerical section for better understanding of transmission dynamics.
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spelling pubmed-78506262021-02-02 Stability analysis and optimal control of Covid-19 pandemic SEIQR fractional mathematical model with harmonic mean type incidence rate and treatment Sinan, Muhammad Ali, Amjad Shah, Kamal Assiri, Taghreed A. Nofal, Taher A. Results Phys Article In the present work, we investigated the transmission dynamics of fractional order SARS-CoV-2 mathematical model with the help of Susceptible [Formula: see text] , Exposed [Formula: see text] , Infected [Formula: see text] , Quarantine [Formula: see text] , and Recovered [Formula: see text]. The aims of this work is to investigate the stability and optimal control of the concerned mathematical model for both local and global stability by third additive compound matrix approach and we also obtained threshold value by the next generation approach. The author’s visualized the desired results graphically. We also control each of the population of underlying model with control variables by optimal control strategies with Pontryagin’s maximum Principle and obtained the desired numerical results by using the homotopy perturbation method. The proposed model is locally asymptotically unstable, while stable globally asymptotically on endemic equilibrium. We also explored the results graphically in numerical section for better understanding of transmission dynamics. The Authors. Published by Elsevier B.V. 2021-03 2021-01-30 /pmc/articles/PMC7850626/ /pubmed/33552882 http://dx.doi.org/10.1016/j.rinp.2021.103873 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Sinan, Muhammad
Ali, Amjad
Shah, Kamal
Assiri, Taghreed A.
Nofal, Taher A.
Stability analysis and optimal control of Covid-19 pandemic SEIQR fractional mathematical model with harmonic mean type incidence rate and treatment
title Stability analysis and optimal control of Covid-19 pandemic SEIQR fractional mathematical model with harmonic mean type incidence rate and treatment
title_full Stability analysis and optimal control of Covid-19 pandemic SEIQR fractional mathematical model with harmonic mean type incidence rate and treatment
title_fullStr Stability analysis and optimal control of Covid-19 pandemic SEIQR fractional mathematical model with harmonic mean type incidence rate and treatment
title_full_unstemmed Stability analysis and optimal control of Covid-19 pandemic SEIQR fractional mathematical model with harmonic mean type incidence rate and treatment
title_short Stability analysis and optimal control of Covid-19 pandemic SEIQR fractional mathematical model with harmonic mean type incidence rate and treatment
title_sort stability analysis and optimal control of covid-19 pandemic seiqr fractional mathematical model with harmonic mean type incidence rate and treatment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850626/
https://www.ncbi.nlm.nih.gov/pubmed/33552882
http://dx.doi.org/10.1016/j.rinp.2021.103873
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