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A serous borderline ovarian tumour in a transgender male adolescent

Here we present a transgender male adolescent with an androgen receptor-positive serous borderline ovarian tumour in the setting of testosterone treatment for medical gender transition. To our knowledge, this is the second report of borderline tumour in a transgender individual and the first in an a...

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Detalles Bibliográficos
Autores principales: Millington, Kate, Hayes, Katherine, Pilcher, Sarah, Roberts, Stephanie, Vargas, Sara O., French, Amanda, Veneris, Jennifer, O’Neill, Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851115/
https://www.ncbi.nlm.nih.gov/pubmed/33106582
http://dx.doi.org/10.1038/s41416-020-01129-4
Descripción
Sumario:Here we present a transgender male adolescent with an androgen receptor-positive serous borderline ovarian tumour in the setting of testosterone treatment for medical gender transition. To our knowledge, this is the second report of borderline tumour in a transgender individual and the first in an adolescent, an age group in which borderline tumours are extremely rare. We discuss the specific considerations of treating ovarian tumours in the transgender male population, the incompletely understood role of androgens in the genesis of ovarian epithelial neoplasia, and an emphasis on assessing cancer risk in transgender patients based on patient anatomy.