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FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial

BACKGROUND: Cetuximab plus FOLFIRI improved overall survival compared with bevacizumab plus FOLFIRI in KRAS wild-type metastatic colorectal cancer (mCRC) in FIRE-3, but no corresponding benefit was found for progression-free survival. This analysis aimed to determine whether cetuximab improves respo...

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Detalles Bibliográficos
Autores principales:	Heinemann, Volker, von Weikersthal, Ludwig Fischer, Decker, Thomas, Kiani, Alexander, Kaiser, Florian, Al-Batran, Salah-Edin, Heintges, Tobias, Lerchenmüller, Christoph, Kahl, Christoph, Seipelt, Gernot, Kullmann, Frank, Moehler, Markus, Scheithauer, Werner, Held, Swantje, Miller-Phillips, Lisa, Modest, Dominik Paul, Jung, Andreas, Kirchner, Thomas, Stintzing, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851157/ https://www.ncbi.nlm.nih.gov/pubmed/33154570 http://dx.doi.org/10.1038/s41416-020-01140-9

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