Combined effects of genotype and childhood adversity shape variability of DNA methylation across age

Lasting effects of adversity, such as exposure to childhood adversity (CA) on disease risk, may be embedded via epigenetic mechanisms but findings from human studies investigating the main effects of such exposure on epigenetic measures, including DNA methylation (DNAm), are inconsistent. Studies in...

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Detalles Bibliográficos
Autores principales: Czamara, Darina, Tissink, Elleke, Tuhkanen, Johanna, Martins, Jade, Awaloff, Yvonne, Drake, Amanda J., Khulan, Batbayar, Palotie, Aarno, Winter, Sibylle M., Nemeroff, Charles B., Craighead, W. Edward, Dunlop, Boadie W., Mayberg, Helen S., Kinkead, Becky, Mathew, Sanjay J., Iosifescu, Dan V., Neylan, Thomas C., Heim, Christine M., Lahti, Jari, Eriksson, Johan G., Räikkönen, Katri, Ressler, Kerry J., Provençal, Nadine, Binder, Elisabeth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851167/
https://www.ncbi.nlm.nih.gov/pubmed/33526782
http://dx.doi.org/10.1038/s41398-020-01147-z

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