Realising the full potential of MR-PHeWAS in cancer

MR-PHeWAS is a powerful new design for discovering causal mechanisms between a disease and its many candidate risk factors in a hypothesis-free manner. This technique has great potential in the field of cancer research, provided that both powerful and principled statistical approaches are used.

Detalles Bibliográficos
Autor principal: Bowden, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851387/
https://www.ncbi.nlm.nih.gov/pubmed/33235313
http://dx.doi.org/10.1038/s41416-020-01165-0
Descripción
Sumario:MR-PHeWAS is a powerful new design for discovering causal mechanisms between a disease and its many candidate risk factors in a hypothesis-free manner. This technique has great potential in the field of cancer research, provided that both powerful and principled statistical approaches are used.

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