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Realising the full potential of MR-PHeWAS in cancer
MR-PHeWAS is a powerful new design for discovering causal mechanisms between a disease and its many candidate risk factors in a hypothesis-free manner. This technique has great potential in the field of cancer research, provided that both powerful and principled statistical approaches are used.
Autor principal: | |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851387/ https://www.ncbi.nlm.nih.gov/pubmed/33235313 http://dx.doi.org/10.1038/s41416-020-01165-0 |
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author | Bowden, Jack |
author_facet | Bowden, Jack |
author_sort | Bowden, Jack |
collection | PubMed |
description | MR-PHeWAS is a powerful new design for discovering causal mechanisms between a disease and its many candidate risk factors in a hypothesis-free manner. This technique has great potential in the field of cancer research, provided that both powerful and principled statistical approaches are used. |
format | Online Article Text |
id | pubmed-7851387 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-78513872021-11-25 Realising the full potential of MR-PHeWAS in cancer Bowden, Jack Br J Cancer Editorial MR-PHeWAS is a powerful new design for discovering causal mechanisms between a disease and its many candidate risk factors in a hypothesis-free manner. This technique has great potential in the field of cancer research, provided that both powerful and principled statistical approaches are used. Nature Publishing Group UK 2020-11-25 2021-02-02 /pmc/articles/PMC7851387/ /pubmed/33235313 http://dx.doi.org/10.1038/s41416-020-01165-0 Text en © Cancer Research UK 2020 https://creativecommons.org/licenses/by/4.0/ Note This work is published under the standard license to publish agreement. After 12 months the work will become freely available and the license terms will switch to a Creative Commons Attribution 4.0 International (CC BY 4.0). |
spellingShingle | Editorial Bowden, Jack Realising the full potential of MR-PHeWAS in cancer |
title | Realising the full potential of MR-PHeWAS in cancer |
title_full | Realising the full potential of MR-PHeWAS in cancer |
title_fullStr | Realising the full potential of MR-PHeWAS in cancer |
title_full_unstemmed | Realising the full potential of MR-PHeWAS in cancer |
title_short | Realising the full potential of MR-PHeWAS in cancer |
title_sort | realising the full potential of mr-phewas in cancer |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851387/ https://www.ncbi.nlm.nih.gov/pubmed/33235313 http://dx.doi.org/10.1038/s41416-020-01165-0 |
work_keys_str_mv | AT bowdenjack realisingthefullpotentialofmrphewasincancer |