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Trazodone effects on developing brain

Trazodone (TRZ) is a commonly prescribed antidepressant with significant off-label use for insomnia. A recent drug screening revealed that TRZ interferes with sterol biosynthesis, causing elevated levels of sterol precursor 7-dehydrocholesterol (7-DHC). Recognizing the well-documented, disruptive ef...

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Detalles Bibliográficos
Autores principales: Korade, Zeljka, Allen, Luke B., Anderson, Allison, Tallman, Keri A., Genaro-Mattos, Thiago C., Porter, Ned A., Mirnics, Karoly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851398/
https://www.ncbi.nlm.nih.gov/pubmed/33526772
http://dx.doi.org/10.1038/s41398-021-01217-w