Unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled HIV infection

Cryptococcal meningoencephalitis (CM) classically occurs in individuals with advanced HIV infection, solid organ transplants, or other immunocompromising conditions. We report a case of fatal CM in a 78-year-old woman with well-controlled HIV infection who had delayed diagnosis, persistently elevate...

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Autores principales: Yoon, Hyun ah, Riska, Paul F., Jain, Ruchika, Morales, Cariane, Pirofski, Liise-anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851412/
https://www.ncbi.nlm.nih.gov/pubmed/33552883
http://dx.doi.org/10.1016/j.mmcr.2021.01.003
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author Yoon, Hyun ah
Riska, Paul F.
Jain, Ruchika
Morales, Cariane
Pirofski, Liise-anne
author_facet Yoon, Hyun ah
Riska, Paul F.
Jain, Ruchika
Morales, Cariane
Pirofski, Liise-anne
author_sort Yoon, Hyun ah
collection PubMed
description Cryptococcal meningoencephalitis (CM) classically occurs in individuals with advanced HIV infection, solid organ transplants, or other immunocompromising conditions. We report a case of fatal CM in a 78-year-old woman with well-controlled HIV infection who had delayed diagnosis, persistently elevated intracranial pressure and pleocytosis of the cerebrospinal fluid. Initial suspicion for CM was low due to her relatively high CD4(+) T cell counts, which likely contributed to greater inflammation.
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spelling pubmed-78514122021-02-05 Unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled HIV infection Yoon, Hyun ah Riska, Paul F. Jain, Ruchika Morales, Cariane Pirofski, Liise-anne Med Mycol Case Rep Case Report Cryptococcal meningoencephalitis (CM) classically occurs in individuals with advanced HIV infection, solid organ transplants, or other immunocompromising conditions. We report a case of fatal CM in a 78-year-old woman with well-controlled HIV infection who had delayed diagnosis, persistently elevated intracranial pressure and pleocytosis of the cerebrospinal fluid. Initial suspicion for CM was low due to her relatively high CD4(+) T cell counts, which likely contributed to greater inflammation. Elsevier 2021-01-26 /pmc/articles/PMC7851412/ /pubmed/33552883 http://dx.doi.org/10.1016/j.mmcr.2021.01.003 Text en © 2021 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yoon, Hyun ah
Riska, Paul F.
Jain, Ruchika
Morales, Cariane
Pirofski, Liise-anne
Unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled HIV infection
title Unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled HIV infection
title_full Unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled HIV infection
title_fullStr Unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled HIV infection
title_full_unstemmed Unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled HIV infection
title_short Unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled HIV infection
title_sort unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled hiv infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851412/
https://www.ncbi.nlm.nih.gov/pubmed/33552883
http://dx.doi.org/10.1016/j.mmcr.2021.01.003
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