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NGS-based accurate and efficient detection of circulating cell-free mitochondrial DNA in cancer patients

Mitochondrial DNA (mtDNA) mutations are closely implicated in the pathogenesis of multiple cancers, making circulating cell-free mtDNA (ccf-mtDNA) as a potential non-invasive tumor biomarker. However, an effective approach to comprehensively profile ccf-mtDNA mutations is still lacking. In this stud...

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Detalles Bibliográficos
Autores principales:	Liu, Yang, Zhou, Kaixiang, Guo, Shanshan, Wang, Yang, Ji, Xiaoying, Yuan, Qing, Su, Liping, Guo, Xu, Gu, Xiwen, Xing, Jinliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851424/ https://www.ncbi.nlm.nih.gov/pubmed/33575112 http://dx.doi.org/10.1016/j.omtn.2020.12.017

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