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The comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: A cohort study
BACKGROUND: Preterm labor (PTL) is one of the most important factors in neonatal mortality. Some studies have revealed a reverse relationship between cervical length (CL) and PTL, however, further evidence is needed to confirm it. OBJECTIVE: To investigate the predictive value of CL in spontaneous a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Knowledge E
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851474/ https://www.ncbi.nlm.nih.gov/pubmed/33554003 http://dx.doi.org/10.18502/ijrm.v19i1.8180 |
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author | Jafari, Razieh Mohammad Zargar, Mahvash Barati, Mojgan Ershadian, Somayeh |
author_facet | Jafari, Razieh Mohammad Zargar, Mahvash Barati, Mojgan Ershadian, Somayeh |
author_sort | Jafari, Razieh Mohammad |
collection | PubMed |
description | BACKGROUND: Preterm labor (PTL) is one of the most important factors in neonatal mortality. Some studies have revealed a reverse relationship between cervical length (CL) and PTL, however, further evidence is needed to confirm it. OBJECTIVE: To investigate the predictive value of CL in spontaneous and in vitro fertilization (IVF) pregnancies. MATERIALS AND METHODS: This prospective cohort study was performed on 154 pregnant women from 16-26 wk of gestation with singleton fetus in spontaneous delivery (n = 77) and IVF pregnancies (n = 77) and followed up until delivery. Women with multiple pregnancy, placenta previa, cerclage, and congenital anomalies were excluded from study. The cut-off determination was done according to the Roc analysis. RESULTS: The mean CL in term delivery and PTL groups were 37 [Formula: see text] 7 mm and 31 [Formula: see text] 6 mm, respectively (p [Formula: see text] 0.001). The frequency of PTL in spontaneous and IVF pregnancies were 7.8% and 23.27%, respectively (p = 0.007). According to the Roc analysis, the best cut-off for normal pregnancy was [Formula: see text] 36 mm with the negative predictive value of 97.9%, the positive predictive value of 11.4%, sensitivity 83.3%, and specificity of 46.5%. While for the IVF group, the cut off was [Formula: see text] 30 mm, with a negative predictive value of 88.4%, positive predictive value of 57.8%, sensitivity of 63.2%, and specificity of 86%. CONCLUSION: In this study, IVF had a significant direct correlation with PTL. CL also had a significant indirect relationship with PTL. |
format | Online Article Text |
id | pubmed-7851474 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Knowledge E |
record_format | MEDLINE/PubMed |
spelling | pubmed-78514742021-02-05 The comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: A cohort study Jafari, Razieh Mohammad Zargar, Mahvash Barati, Mojgan Ershadian, Somayeh Int J Reprod Biomed Research Article BACKGROUND: Preterm labor (PTL) is one of the most important factors in neonatal mortality. Some studies have revealed a reverse relationship between cervical length (CL) and PTL, however, further evidence is needed to confirm it. OBJECTIVE: To investigate the predictive value of CL in spontaneous and in vitro fertilization (IVF) pregnancies. MATERIALS AND METHODS: This prospective cohort study was performed on 154 pregnant women from 16-26 wk of gestation with singleton fetus in spontaneous delivery (n = 77) and IVF pregnancies (n = 77) and followed up until delivery. Women with multiple pregnancy, placenta previa, cerclage, and congenital anomalies were excluded from study. The cut-off determination was done according to the Roc analysis. RESULTS: The mean CL in term delivery and PTL groups were 37 [Formula: see text] 7 mm and 31 [Formula: see text] 6 mm, respectively (p [Formula: see text] 0.001). The frequency of PTL in spontaneous and IVF pregnancies were 7.8% and 23.27%, respectively (p = 0.007). According to the Roc analysis, the best cut-off for normal pregnancy was [Formula: see text] 36 mm with the negative predictive value of 97.9%, the positive predictive value of 11.4%, sensitivity 83.3%, and specificity of 46.5%. While for the IVF group, the cut off was [Formula: see text] 30 mm, with a negative predictive value of 88.4%, positive predictive value of 57.8%, sensitivity of 63.2%, and specificity of 86%. CONCLUSION: In this study, IVF had a significant direct correlation with PTL. CL also had a significant indirect relationship with PTL. Knowledge E 2021-01-25 /pmc/articles/PMC7851474/ /pubmed/33554003 http://dx.doi.org/10.18502/ijrm.v19i1.8180 Text en Copyright © 2021 Mohammad Jafari et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Research Article Jafari, Razieh Mohammad Zargar, Mahvash Barati, Mojgan Ershadian, Somayeh The comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: A cohort study |
title | The comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: A cohort study |
title_full | The comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: A cohort study |
title_fullStr | The comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: A cohort study |
title_full_unstemmed | The comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: A cohort study |
title_short | The comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: A cohort study |
title_sort | comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: a cohort study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851474/ https://www.ncbi.nlm.nih.gov/pubmed/33554003 http://dx.doi.org/10.18502/ijrm.v19i1.8180 |
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