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Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways
Cisplatin is currently used to treat inoperable recurrent meningiomas, but its side effects and drug resistance limit its use. Metformin has recently been identified as a chemosensitizing agent. However, the combined treatment of cisplatin and metformin in high-grade meningiomas has not been reporte...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851485/ https://www.ncbi.nlm.nih.gov/pubmed/33575476 http://dx.doi.org/10.1016/j.omto.2020.11.004 |