Modulation of mTOR and epigenetic pathways as therapeutics in gallbladder cancer

Gallbladder cancer (GBC) is the most common malignancy of the biliary tract, with extremely dismal prognosis. Limited therapeutic options are available for GBC patients. We used whole-exome sequencing of human GBC to identify the ErbB and epigenetic pathways as two vulnerabilities in GBC. We screene...

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Detalles Bibliográficos
Autores principales: Yang, Dong, Chen, Tao, Zhan, Ming, Xu, Sunwang, Yin, Xiangfan, Liu, Qin, Chen, Wei, Zhang, Yunhe, Liu, Dejun, Yan, Jinchun, Huang, Qihong, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851494/
https://www.ncbi.nlm.nih.gov/pubmed/33575471
http://dx.doi.org/10.1016/j.omto.2020.11.007

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