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The AKT/GSK3β-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1

Although oxaliplatin serves as one of the first-line drugs prescribed for treating colorectal cancer (CRC), the therapeutic effect is disappointing due to drug resistance. So far, the molecular mechanisms mediating oxaliplatin resistance remain unclear. In this study, we found the chemoresistance in...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Ma, Xiao-Dong, Jiang, Guan-Min, Shi, Bin, Zhong, Wen, Sun, Chun-Lei, Zhao, Liang, Hou, Yan-Jiao, Wang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851510/
https://www.ncbi.nlm.nih.gov/pubmed/32331534
http://dx.doi.org/10.3727/096504020X15877284857868