Cargando…
The AKT/GSK3β-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1
Although oxaliplatin serves as one of the first-line drugs prescribed for treating colorectal cancer (CRC), the therapeutic effect is disappointing due to drug resistance. So far, the molecular mechanisms mediating oxaliplatin resistance remain unclear. In this study, we found the chemoresistance in...
Autores principales: | Wei, Wei, Ma, Xiao-Dong, Jiang, Guan-Min, Shi, Bin, Zhong, Wen, Sun, Chun-Lei, Zhao, Liang, Hou, Yan-Jiao, Wang, Hao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cognizant Communication Corporation
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851510/ https://www.ncbi.nlm.nih.gov/pubmed/32331534 http://dx.doi.org/10.3727/096504020X15877284857868 |
Ejemplares similares
-
Upregulation of ERCC1 and DPD expressions after oxaliplatin-based first-line chemotherapy for metastatic colorectal cancer
por: Baba, H, et al.
Publicado: (2012) -
KIF11 is upregulated in colorectal cancer and silencing of it impairs tumor growth and sensitizes colorectal cancer cells to oxaliplatin via p53/GSK3β signaling
por: Zhou, Yan, et al.
Publicado: (2021) -
GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway
por: Feng, Ying, et al.
Publicado: (2021) -
SHED-derived exosomes ameliorate hyposalivation caused by Sjögren's syndrome via Akt/GSK-3β/Slug-mediated ZO-1 expression
por: Du, Zhihao, et al.
Publicado: (2023) -
IGHG1 upregulation promoted gastric cancer malignancy via AKT/GSK-3β/β-Catenin pathway
por: Li, Xinyu, et al.
Publicado: (2021)