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Fzd2 Contributes to Breast Cancer Cell Mesenchymal-Like Stemness and Drug Resistance

Cancer cell stemness is responsible for cancer relapse, distal metastasis, and drug resistance. Here we identified that Frizzled 2 (Fzd2), one member of Wnt receptor Frizzled family, induced human breast cancer (BC) cell stemness via noncanonical Wnt pathways. Fzd2 was overexpressed in human BC tiss...

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Detalles Bibliográficos
Autores principales: Yin, Ping, Wang, Wei, Gao, Jian, Bai, Yu, Wang, Zhuo, Na, Lei, Sun, Yu, Zhao, Chenghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851528/
https://www.ncbi.nlm.nih.gov/pubmed/31907106
http://dx.doi.org/10.3727/096504020X15783052025051

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