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The Human Adenovirus 2 Transcriptome: an Amazing Complexity of Alternatively Spliced mRNAs

We used the Nanopore long-read sequencing platform to demonstrate how amazingly complex the human adenovirus type 2 (Ad2) transcriptome is, with a flexible splicing machinery producing a range of novel mRNAs from both the early and late transcription units. In total, we report more than 900 alternat...

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Detalles Bibliográficos
Autores principales: Westergren Jakobsson, Amanda, Segerman, Bo, Wallerman, Ola, Bergström Lind, Sara, Zhao, Hongxing, Rubin, Carl-Johan, Pettersson, Ulf, Akusjärvi, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851563/
https://www.ncbi.nlm.nih.gov/pubmed/33239457
http://dx.doi.org/10.1128/JVI.01869-20