Cargando…

Phenoxythiophene sulfonamide compound B355252 protects neuronal cells against glutamate-induced excitotoxicity by attenuating mitochondrial fission and the nuclear translocation of AIF

Glutamate neurotoxicity has been implicated in the initiation and progression of various neurological and neurodegenerative disorders. Therefore, it is necessary to develop therapeutics for the treatment of patients with these devastating diseases. Mitochondrial fission plays an import role in the m...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yuxin, Gliyazova, Nailya S., Li, P. Andy, Ibeanu, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851598/
https://www.ncbi.nlm.nih.gov/pubmed/33603830
http://dx.doi.org/10.3892/etm.2021.9652