Koumine Suppresses IL-1β Secretion and Attenuates Inflammation Associated With Blocking ROS/NF-κB/NLRP3 Axis in Macrophages

Koumine (KM), one of the primary constituents of Gelsemium elegans, has been used for the treatment of inflammatory diseases such as rheumatoid arthritis, but whether KM impacts the activation of the NOD-like receptor protein 3 (NLRP3) inflammasome remains unknown. This study aimed to explore the in...

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Detalles Bibliográficos
Autores principales: Luo, Yufei, Xiong, Bojun, Liu, Haiping, Chen, Zehong, Huang, Huihui, Yu, Changxi, Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851739/
https://www.ncbi.nlm.nih.gov/pubmed/33542692
http://dx.doi.org/10.3389/fphar.2020.622074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851739/
https://www.ncbi.nlm.nih.gov/pubmed/33542692
http://dx.doi.org/10.3389/fphar.2020.622074

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