Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment

In the randomised TARGIT-A trial, risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy was non-inferior to whole-breast external beam radiotherapy, for local recurrence. In the long-term, no difference was found in any breast cancer outcome, whereas there were fewer deat...

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Autores principales: Vaidya, Jayant S., Bulsara, Max, Baum, Michael, Tobias, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851812/
https://www.ncbi.nlm.nih.gov/pubmed/33531693
http://dx.doi.org/10.1038/s41416-020-01233-5
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author Vaidya, Jayant S.
Bulsara, Max
Baum, Michael
Tobias, Jeffrey S.
author_facet Vaidya, Jayant S.
Bulsara, Max
Baum, Michael
Tobias, Jeffrey S.
author_sort Vaidya, Jayant S.
collection PubMed
description In the randomised TARGIT-A trial, risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy was non-inferior to whole-breast external beam radiotherapy, for local recurrence. In the long-term, no difference was found in any breast cancer outcome, whereas there were fewer deaths from non-breast-cancer causes. TARGIT-IORT should be included in pre-operative consultations with eligible patients.
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spelling pubmed-78518122021-02-02 Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment Vaidya, Jayant S. Bulsara, Max Baum, Michael Tobias, Jeffrey S. Br J Cancer Comment In the randomised TARGIT-A trial, risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy was non-inferior to whole-breast external beam radiotherapy, for local recurrence. In the long-term, no difference was found in any breast cancer outcome, whereas there were fewer deaths from non-breast-cancer causes. TARGIT-IORT should be included in pre-operative consultations with eligible patients. Nature Publishing Group UK 2021-02-02 2021-04-27 /pmc/articles/PMC7851812/ /pubmed/33531693 http://dx.doi.org/10.1038/s41416-020-01233-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
Vaidya, Jayant S.
Bulsara, Max
Baum, Michael
Tobias, Jeffrey S.
Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment
title Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment
title_full Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment
title_fullStr Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment
title_full_unstemmed Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment
title_short Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment
title_sort single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851812/
https://www.ncbi.nlm.nih.gov/pubmed/33531693
http://dx.doi.org/10.1038/s41416-020-01233-5
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