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Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion
Epithelia can eliminate apoptotic cells by apical extrusion. This is a complex morphogenetic event where expulsion of the apoptotic cell is accompanied by rearrangement of its immediate neighbors to form a rosette. A key mechanism for extrusion is constriction of an actomyosin network that neighbor...
Autores principales: | Teo, Jessica L., Tomatis, Vanesa M., Coburn, Luke, Lagendijk, Anne K., Schouwenaar, Irin-Maya, Budnar, Srikanth, Hall, Thomas E., Verma, Suzie, McLachlan, Robert W., Hogan, Benjamin M., Parton, Robert G., Yap, Alpha S., Gomez, Guillermo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851871/ https://www.ncbi.nlm.nih.gov/pubmed/32903148 http://dx.doi.org/10.1091/mbc.E20-01-0084 |
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