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β-actin contributes to open chromatin for activation of the adipogenic pioneer factor CEBPA during transcriptional reprograming
Adipogenesis is regulated by a cascade of signals that drive transcriptional reprogramming in adipocytes. Here, we report that nuclear actin regulates the chromatin states that establish tissue- specific expression during adipogenesis. To study the role of β-actin in adipocyte differentiation, we co...
Autores principales: | Al-Sayegh, M. A., Mahmood, S. R., Khair, S. B. Abul, Xie, X., El Gindi, M., Kim, T., Almansoori, A., Percipalle, P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851876/ https://www.ncbi.nlm.nih.gov/pubmed/32877276 http://dx.doi.org/10.1091/mbc.E19-11-0628 |
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