CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer

BACKGROUND: E3 ubiquitin ligase HRD1 (HMG-CoA reductase degradation protein 1, alias synoviolin with SYVN1 as the official gene symbol) was found downregulated and acting as a tumor suppressor in breast cancer, while the exact expression profile of HRD1 in different breast cancer subtypes remains un...

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Detalles Bibliográficos
Autores principales: Fan, Ya, Wang, Jia, Jin, Wen, Sun, Yifei, Xu, Yuemei, Wang, Yipin, Liang, Xiubin, Su, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851937/
https://www.ncbi.nlm.nih.gov/pubmed/33530981
http://dx.doi.org/10.1186/s12943-021-01321-x

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