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Three-dimensional Pulmonary Monitoring Using Focused Electrical Impedance Measurements

Lung pathologies such as edema, atelectasis or pneumonia are potentially life threatening conditions. Especially in critically ill and mechanically ventilated patients, an early diagnosis and treatment is crucial to prevent an Acute Respiratory Distress Syndrome [1]. Thus, continuous monitoring tool...

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Detalles Bibliográficos
Autores principales: Orschulik, Jakob, Pokee, Diana, Menden, Tobias, Leonhardt, Steffen, Walter, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852007/
https://www.ncbi.nlm.nih.gov/pubmed/33584924
http://dx.doi.org/10.2478/joeb-2018-0013
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author Orschulik, Jakob
Pokee, Diana
Menden, Tobias
Leonhardt, Steffen
Walter, Marian
author_facet Orschulik, Jakob
Pokee, Diana
Menden, Tobias
Leonhardt, Steffen
Walter, Marian
author_sort Orschulik, Jakob
collection PubMed
description Lung pathologies such as edema, atelectasis or pneumonia are potentially life threatening conditions. Especially in critically ill and mechanically ventilated patients, an early diagnosis and treatment is crucial to prevent an Acute Respiratory Distress Syndrome [1]. Thus, continuous monitoring tool for the lung condition available at the bedside would be highly appreciated. One concept for this is Electrical Impedance Tomography (EIT). In EIT, an electrode belt of typically 16 or 32 electrodes is attached at the body surface and multiple impedance measurements are performed. From this, the conductivity change inside the body is reconstructed in a two-dimensional image. In various studies, EIT proved to be a useful tool for quantifying recruitment maneuvers, the assessment of the ventilation homogeneity, the detection of lung edema or perfusion monitoring [2, 3, 4, 5]. Nevertheless, the main problem of EIT is the low spatial resolution (compared to CT) and the limitation to two dimensional images. In this paper, we try to address the latter issue: Instead of projecting conductivity changes onto a two-dimensional image, we adjust electrode positions to focus single tetrapolar measurements to specific, three-dimensional regions of interest. In earlier work, we defined guidelines to achieve this focusing [6, 7]. In this paper, we demonstrate in simulations and in a water tank experiment that applying these guidelines can help to detect pathologies in specific lung regions.
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spelling pubmed-78520072021-02-11 Three-dimensional Pulmonary Monitoring Using Focused Electrical Impedance Measurements Orschulik, Jakob Pokee, Diana Menden, Tobias Leonhardt, Steffen Walter, Marian J Electr Bioimpedance Research Articles Lung pathologies such as edema, atelectasis or pneumonia are potentially life threatening conditions. Especially in critically ill and mechanically ventilated patients, an early diagnosis and treatment is crucial to prevent an Acute Respiratory Distress Syndrome [1]. Thus, continuous monitoring tool for the lung condition available at the bedside would be highly appreciated. One concept for this is Electrical Impedance Tomography (EIT). In EIT, an electrode belt of typically 16 or 32 electrodes is attached at the body surface and multiple impedance measurements are performed. From this, the conductivity change inside the body is reconstructed in a two-dimensional image. In various studies, EIT proved to be a useful tool for quantifying recruitment maneuvers, the assessment of the ventilation homogeneity, the detection of lung edema or perfusion monitoring [2, 3, 4, 5]. Nevertheless, the main problem of EIT is the low spatial resolution (compared to CT) and the limitation to two dimensional images. In this paper, we try to address the latter issue: Instead of projecting conductivity changes onto a two-dimensional image, we adjust electrode positions to focus single tetrapolar measurements to specific, three-dimensional regions of interest. In earlier work, we defined guidelines to achieve this focusing [6, 7]. In this paper, we demonstrate in simulations and in a water tank experiment that applying these guidelines can help to detect pathologies in specific lung regions. Sciendo 2018-12-31 /pmc/articles/PMC7852007/ /pubmed/33584924 http://dx.doi.org/10.2478/joeb-2018-0013 Text en © 2018 Orschulik J, Pokee D, Menden T, Leonhardt S, Walter M published by Sciendo http://creativecommons.org/licenses/by-nc-nd/3.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
spellingShingle Research Articles
Orschulik, Jakob
Pokee, Diana
Menden, Tobias
Leonhardt, Steffen
Walter, Marian
Three-dimensional Pulmonary Monitoring Using Focused Electrical Impedance Measurements
title Three-dimensional Pulmonary Monitoring Using Focused Electrical Impedance Measurements
title_full Three-dimensional Pulmonary Monitoring Using Focused Electrical Impedance Measurements
title_fullStr Three-dimensional Pulmonary Monitoring Using Focused Electrical Impedance Measurements
title_full_unstemmed Three-dimensional Pulmonary Monitoring Using Focused Electrical Impedance Measurements
title_short Three-dimensional Pulmonary Monitoring Using Focused Electrical Impedance Measurements
title_sort three-dimensional pulmonary monitoring using focused electrical impedance measurements
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852007/
https://www.ncbi.nlm.nih.gov/pubmed/33584924
http://dx.doi.org/10.2478/joeb-2018-0013
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