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Title: insoluble proteins catch heterologous soluble proteins into inclusion bodies by intermolecular interaction of aggregating peptides
BACKGROUND: Protein aggregation is a biological event observed in expression systems in which the recombinant protein is produced under stressful conditions surpassing the homeostasis of the protein quality control system. In addition, protein aggregation is also related to conformational diseases i...
Autores principales: | Carratalá, Jose Vicente, Cisneros, Andrés, Hellman, Elijah, Villaverde, Antonio, Ferrer-Miralles, Neus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852131/ https://www.ncbi.nlm.nih.gov/pubmed/33531005 http://dx.doi.org/10.1186/s12934-021-01524-3 |
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