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Haploflow: Strain-resolved de novo assembly of viral genomes

In viral infections often multiple related viral strains are present, due to coinfection or within-host evolution. We describe Haploflow, a de Bruijn graph-based assembler for de novo genome assembly of viral strains from mixed sequence samples using a novel flow algorithm. We assessed Haploflow acr...

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Detalles Bibliográficos
Autores principales:	Fritz, A., Bremges, A., Deng, Z.-L., Lesker, T.-R., Götting, J., Ganzenmüller, T., Sczyrba, A., Dilthey, A., Klawonn, F., McHardy, A.C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852260/ https://www.ncbi.nlm.nih.gov/pubmed/33532769 http://dx.doi.org/10.1101/2021.01.25.428049

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