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Molecular size-dependent specificity of hyaluronan on functional properties, morphology and matrix composition of mammary cancer cells

High levels of hyaluronan (ΗΑ), a major extracellular matrix (ECM) glycosaminoglycan, have been correlated with poor clinical outcome in several malignancies, including breast cancer. The high and low molecular weight HΑ forms exert diverse biological functions. Depending on their molecular size, ΗΑ...

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Detalles Bibliográficos
Autores principales: Tavianatou, Anastasia-Gerasimoula, Piperigkou, Zoi, Barbera, Carlo, Beninatto, Riccardo, Masola, Valentina, Caon, Ilaria, Onisto, Maurizio, Franchi, Marco, Galesso, Devis, Karamanos, Nikos K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852304/
https://www.ncbi.nlm.nih.gov/pubmed/33543007
http://dx.doi.org/10.1016/j.mbplus.2019.100008