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Native extracellular matrix, synthesized ex vivo by bone marrow or adipose stromal cells, faithfully directs mesenchymal stem cell differentiation

Mesenchymal stem cells (MSCs) are highly responsive to cues in the microenvironment (niche) that must be recapitulated ex vivo to study their authentic behavior. In this study, we hypothesized that native bone marrow (BM)- and adipose (AD)-derived extracellular matrices (ECM) were unique in their ab...

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Detalles Bibliográficos
Autores principales: Marinkovic, Milos, Tran, Olivia N., Block, Travis J., Rakian, Rubie, Gonzalez, Aaron O., Dean, David D., Yeh, Chih-Ko, Chen, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852316/
https://www.ncbi.nlm.nih.gov/pubmed/33543037
http://dx.doi.org/10.1016/j.mbplus.2020.100044