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Elevated glucose alters global gene expression and tenascin-C alternative splicing in mesangial cells
Mesangial cells are the major extracellular matrix (ECM)-producing cells in the kidney glomerulus and, when exposed to elevated glucose levels, they up-regulate assembly of fibronectin (FN) and other ECM proteins. Increases in glucose concentration are known to alter gene expression; here we investi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852322/ https://www.ncbi.nlm.nih.gov/pubmed/33543041 http://dx.doi.org/10.1016/j.mbplus.2020.100048 |