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Elevated glucose alters global gene expression and tenascin-C alternative splicing in mesangial cells

Mesangial cells are the major extracellular matrix (ECM)-producing cells in the kidney glomerulus and, when exposed to elevated glucose levels, they up-regulate assembly of fibronectin (FN) and other ECM proteins. Increases in glucose concentration are known to alter gene expression; here we investi...

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Detalles Bibliográficos
Autores principales: Vega, Maria E., Finlay, John B., Vasishtha, Mansi, Schwarzbauer, Jean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852322/
https://www.ncbi.nlm.nih.gov/pubmed/33543041
http://dx.doi.org/10.1016/j.mbplus.2020.100048

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