The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase

The methyltransferase SET domain–containing 2 (SETD2) was originally identified as Huntingtin (HTT) yeast partner B. However, a SETD2 function associated with the HTT scaffolding protein has not been elucidated, and no linkage between HTT and methylation has yet been uncovered. Here, we show that SE...

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Detalles Bibliográficos
Autores principales: Seervai, Riyad N. H., Jangid, Rahul K., Karki, Menuka, Tripathi, Durga Nand, Jung, Sung Yun, Kearns, Sarah E., Verhey, Kristen J., Cianfrocco, Michael A., Millis, Bryan A., Tyska, Matthew J., Mason, Frank M., Rathmell, W. Kimryn, Park, In Young, Dere, Ruhee, Walker, Cheryl Lyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852384/
https://www.ncbi.nlm.nih.gov/pubmed/33008892
http://dx.doi.org/10.1126/sciadv.abb7854

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