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Simultaneous debridement, Ilizarov reconstruction and free muscle flaps in the management of complex tibial infection

Chronic bone infections often present with complex bone and soft tissue loss. Management is difficult and commonly delivered in multiple stages over many months. This study investigated the feasibility and clinical outcomes of reconstruction in one stage. Fifty-seven consecutive patients with chroni...

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Autores principales: Mifsud, Max, Ferguson, Jamie Y., Stubbs, David A., Ramsden, Alex J., McNally, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Copernicus GmbH 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852407/
https://www.ncbi.nlm.nih.gov/pubmed/33552880
http://dx.doi.org/10.5194/jbji-6-63-2020
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author Mifsud, Max
Ferguson, Jamie Y.
Stubbs, David A.
Ramsden, Alex J.
McNally, Martin A.
author_facet Mifsud, Max
Ferguson, Jamie Y.
Stubbs, David A.
Ramsden, Alex J.
McNally, Martin A.
author_sort Mifsud, Max
collection PubMed
description Chronic bone infections often present with complex bone and soft tissue loss. Management is difficult and commonly delivered in multiple stages over many months. This study investigated the feasibility and clinical outcomes of reconstruction in one stage. Fifty-seven consecutive patients with chronic osteomyelitis ([Formula: see text]) or infected non-union ([Formula: see text]) were treated with simultaneous debridement, Ilizarov method and free muscle flap transfer. 41 patients (71.9 %) had systemic co-morbidities (Cierny-Mader group Bs hosts). Infection was confirmed with strict criteria. 48 patients (84.2 %) had segmental defects. The primary outcome was eradication of infection at final follow-up. Secondary outcomes included bone union, flap survival and complications or re-operation related to the reconstruction. Infection was eradicated in [Formula: see text] cases (96.5 %) at a mean follow-up of 36 months (range 12–146). No flap failures occurred during distraction but 6 required early anastomotic revision and 3 were not salvageable (flap failure rate 5.3 %). Bony union was achieved in [Formula: see text] (91.2 %) with the initial surgery alone. After treatment of the five un-united docking sites, all cases achieved bony union at final follow-up. Simultaneous reconstruction with Ilizarov method and free tissue transfer is safe but requires careful planning and logistic considerations. The outcomes from this study are equivalent or better than those reported after staged surgery.
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spelling pubmed-78524072021-02-04 Simultaneous debridement, Ilizarov reconstruction and free muscle flaps in the management of complex tibial infection Mifsud, Max Ferguson, Jamie Y. Stubbs, David A. Ramsden, Alex J. McNally, Martin A. J Bone Jt Infect Original Full-Length Article Chronic bone infections often present with complex bone and soft tissue loss. Management is difficult and commonly delivered in multiple stages over many months. This study investigated the feasibility and clinical outcomes of reconstruction in one stage. Fifty-seven consecutive patients with chronic osteomyelitis ([Formula: see text]) or infected non-union ([Formula: see text]) were treated with simultaneous debridement, Ilizarov method and free muscle flap transfer. 41 patients (71.9 %) had systemic co-morbidities (Cierny-Mader group Bs hosts). Infection was confirmed with strict criteria. 48 patients (84.2 %) had segmental defects. The primary outcome was eradication of infection at final follow-up. Secondary outcomes included bone union, flap survival and complications or re-operation related to the reconstruction. Infection was eradicated in [Formula: see text] cases (96.5 %) at a mean follow-up of 36 months (range 12–146). No flap failures occurred during distraction but 6 required early anastomotic revision and 3 were not salvageable (flap failure rate 5.3 %). Bony union was achieved in [Formula: see text] (91.2 %) with the initial surgery alone. After treatment of the five un-united docking sites, all cases achieved bony union at final follow-up. Simultaneous reconstruction with Ilizarov method and free tissue transfer is safe but requires careful planning and logistic considerations. The outcomes from this study are equivalent or better than those reported after staged surgery. Copernicus GmbH 2020-12-22 /pmc/articles/PMC7852407/ /pubmed/33552880 http://dx.doi.org/10.5194/jbji-6-63-2020 Text en Copyright: © 2020 Max Mifsud et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/
spellingShingle Original Full-Length Article
Mifsud, Max
Ferguson, Jamie Y.
Stubbs, David A.
Ramsden, Alex J.
McNally, Martin A.
Simultaneous debridement, Ilizarov reconstruction and free muscle flaps in the management of complex tibial infection
title Simultaneous debridement, Ilizarov reconstruction and free muscle flaps in the management of complex tibial infection
title_full Simultaneous debridement, Ilizarov reconstruction and free muscle flaps in the management of complex tibial infection
title_fullStr Simultaneous debridement, Ilizarov reconstruction and free muscle flaps in the management of complex tibial infection
title_full_unstemmed Simultaneous debridement, Ilizarov reconstruction and free muscle flaps in the management of complex tibial infection
title_short Simultaneous debridement, Ilizarov reconstruction and free muscle flaps in the management of complex tibial infection
title_sort simultaneous debridement, ilizarov reconstruction and free muscle flaps in the management of complex tibial infection
topic Original Full-Length Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852407/
https://www.ncbi.nlm.nih.gov/pubmed/33552880
http://dx.doi.org/10.5194/jbji-6-63-2020
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